王子月

职称：

副教授

专业：

分析化学

博（硕）导：

硕士生导师

最终学历：

博士研究生

联系电话：

18396853322

电子邮件：

wangzy123@qq.com

简历及研究领域

个人简介：

王子月，女，1993年出生，理学博士。2016年毕业于山东师范大学化学化工与材料科学37000cm威尼斯，获理学学士学位；之后继续在山东师范大学专修分析化学专业，2021年获理学博士学位并于同年留校任教至今。主要从事分析化学、生物化学等领域的课题研究。在基于量子点的单分子检测和疾病生物标志物的超灵敏检测等方面取得了系列科研成果。在Chem. Sci., Anal.   Chem., Chem. Comm.等国际知名学术期刊上以（共同）第一作者身份发表论文17篇。

团队常年招收本科、硕士、博士研究生，欢迎具有化学、生物、医学或材料背景的学生加入我们。期待你的到来。

代表性论文

1、Zi-yue Wang^# , Dong-ling Li^# , Xiaorui Tian^#, Chun-yang Zhang^*. A copper-free and enzyme-free click chemistry-mediated single quantum dot nanosensor for accurate detection of microRNAs in cancer cells and tissues. Chemical Science, 2021, 12(31): 10426-10435.

2、Zi-yue Wang^#, Li-juan Wang^#, Qianyi Zhang^#, Bo Tang^*, Chun-yang Zhang^*, Single quantum dot-based nanosensor for sensitive detection of 5-methylcytosine at both CpG and non-CpG sites. Chemical Science, 2018,9, 1330-1338.

3、Zi-yue Wang^#, Peng Li^#, Lin Cui, Qinfeng Xu, Chun-yang Zhang^*. Construction of a Universal and Label-Free Chemiluminescent Sensor for Accurate Quantification of Both Bacteria and Human Methyltransferases. Analytical Chemistry, 2020,92,13573-13580.

4、Zi-yue Wang^#,Dong-ling Li^#, Xiao-tui Tian^#, Yue-ying Li^*, Chun-yang Zhang^*. Single-Molecule Counting of FTO in Human Breast Tissues Based on a Rolling Circle Transcription Amplification-Driven Clustered Regularly Interspaced Short Palindromic Repeat─ Cas12a. Analytical Chemistry, 2022, 94(32): 11425-11432.

5、Zi-yue Wang^#, Hui-min Yuan^#, Dong-ling Li, Juan Hu^*,Jian-ge Qiu^*, Chun-yang Zhang^*. Hydroxymethylation-Specific Ligation-Mediated Single Quantum Dot-Based Nanosensors for Sensitive Detection of 5-Hydroxymethylcytosine in Cancer Cells. Analytical Chemistry, 2022, 94(27): 9785-9792.

6、Zi-yue Wang^#, Peng Li^#, Jin-ping Hu^#, Qin-feng Xu^*, Chun-yang Zhang^*. Construction of a Single-Molecule Biosensor for Antibody-Free Detection of Locus-Specific N 6-Methyladenosine in Cancer Cells and Tissues. Analytical Chemistry, 2023, 95(12): 5454-5462.

7、Zi-yue Wang^#, Peng Li^#, Lin Cui^#, Jian-Ge Qiu , BingHua Jiang^*, Chun-yang Zhang^*. Integration of nanomaterials with nucleic acid amplification approaches for biosensing. Trends in Analytical Chemistry, 2020,129,115959.

8、Zi-yue Wang^#, Cheng-peng Zhang^#, Chun-yang Zhang^*. Integration of a peptide-DNA conjugate with multiple cyclic signal amplification for the ultrasensitive detection of cathepsin B activity. Chemical Communications, 2020,56,2119-2122.

9、Zi-yue Wang^#, Meng Wang^#, Yan Zhang^#, Chun-yang Zhang^*，Sensitive and label-free discrimination of 5-hydroxymethylcytosine and 5-methylcytosine in DNA by ligation-mediated rolling circle amplification，Chemical Communications, 2018,54, 8602-8605.

10、Zi-yue Wang^#, Ya-ru Meng^#, Jinping Hu^#, Jian-Ge Qiu^* and Chun-yang Zhang^*. Development of a single-molecule biosensor with an ultra-low background for the simultaneous detection of multiple retroviral DNAs. Journal of Materials Chemistry B, 2022, 10(28): 5465-5472.

11、Li C^#, Zi-yue Wang^#, Wang L^*, Chun-yang Zhang^*. Biosensors for epigenetic biomarkers detection: A review. Biosensors and Bioelectronics, 2019: 111695.

12、Li-juanWang^#, Zi-yue Wang^#, Qianyi Zhang, Bo Tang^*, Chun-yang Zhang^*, Cyclic enzymatic repairing-mediated dual-signal amplification for real-time monitoring of thymine DNA glycosylase. Chemical Communications 2017, 53(27), 3878-3881.  

13、Juan Hu^#, Zi-yue Wang^#, Chen-chen Li^#, Chun-yang Zhang^*. Advances in single quantumdot-based nanosensors. Chemical Communications, 2017, 53(100), 13284-13295.

14、Xiaoxia Han^#, Yueying Li^#, Zi-Yue Wang^#, Ling-Zhi Liu, Jian-Ge Qiu, Bing-Jie Liu ^*，Chun-yang Zhang^*. Label-free and sensitive detection of RNA demethylase FTO with primer generation rolling circle amplification. Chemical Communications, 2022, 58(10): 1565-1568.

15、Fei Ma^#, Meng Liu^#, Zi-yue Wang^#, Chun-yang Zhang^*. Multiplex detection of histone-modifying enzymes by total internal reflection fluorescence-based single-molecule detection. Chemical Communications, 2016, 52(6): 1218-1221.  

16、Panyue Li^#, Zi-yue Wang^#*, yue-ying Li, Ling-zhi Liu, Jian-ge Qiu^*, Chun-yang Zhang^*. Bsu polymerase-mediated fluorescence coding for rapid and sensitive detection of 8-oxo-7, 8-dihydroguanine in telomeres of cancer cells. Talanta, 2022, 243: 123340.

17、Li-juan Wang^#, Zi-yue Wang^#, Chun-yang Zhang^*, Primer dephosphorylation-initiated circular exponential amplification for ultrasensitive detection of alkaline phosphatase. Analyst, 2018,143, 4606-4613.

研究课题

国家自然科学基金青年基金2023.01-2025.12

主持，在研