李艳华

职称：

副教授

专业：

分析化学

博（硕）导：

硕导

最终学历：

博士研究生

联系电话：

15376410900

电子邮件：

573162191@qq.com;

liyanhua@sdnu.edu.cn

简历及研究领域

个人简介：

2020年12月于山东师范大学获理学博士学位，2021年3月至今于山东师范大学化学化工与材料科学37000cm威尼斯工作。主讲课程：《分析化学实验》《仪器分析化学实验》。

研究领域：

主要围绕“肿瘤的免疫治疗及细胞活性物质的检测和成像”开展研究工作，相关研究已在Adv. Funct. Mater., Chem. Sci., Anal. Chem., Chem. Commun.等国际著名刊物发表文章20余篇。目前主持国家自然科学基金青年项目1项、山东省自然科学基金青年基金1项。

招生信息：

每年在分析化学专业招收学硕1-2名，在材料与化工专业招收专硕1-2名，欢迎报考！

代表性论文

1. Yanhua Li, Xia Zhang, Xiuyan Wan, Xiaohan Liu, Wei Pan, Na Li*, and Bo Tang*, Inducing Endoplasmic Reticulum Stress to Expose Immunogens: A DNA Tetrahedron Nanoregulator for Enhanced Immunotherapy. Adv. Funct. Mater., 2020, 30 (48), 2000532.

2. Yanhua Li†, Xiaohan Liu†, Xia Zhang, Wei Pan, Na Li,* and Bo Tang*, Immune Cycle-Based Strategies for Cancer Immunotherapy. Adv. Funct. Mater., 2021, 31 (50), 2107540.

3. Yanhua Li, Shaohua Gong, Wei Pan, Yuanyuan Chen, Bo Liu, Na Li*, and Bo Tang*, A tumor acidity activatable and Ca²⁺-assisted immuno-nanoagent enhances breast cancer therapy and suppresses cancer recurrence. Chem. Sci., 2020, 11 (28), 7429-7437.

4. Yanhua Li†, Kun Tang†, Xia Zhang, Wei Pan, Na Li*, and Bo Tang*, A dendritic cell-like biomimetic nanoparticle enhances T cell activation for breast cancer immunotherapy. Chem. Sci., 2022, 13 (1), 105-110.

5. Yanhua Li†, Xia Zhang†, Xiaohan Liu, Wei Pan, Na Li*, and Bo Tang*, Intelligent stimuli-responsive nano immunomodulators for cancer immunotherapy. Chem. Sci., 2021, 12 (9), 3130-3145.

6. Kun Tang†, Xia Zhang†, Jiaqi Yin, Wei Pan, Yanhua Li*, Na Li*, and Bo Tang*, A CaCO₃-based synergistic immunotherapy strategy for treating primary and distal tumors. Chem. Commun., 2023, 59 (24), 3562-3565.

7. Xia Zhang, Jiaqi Yin, Wei Pan, Yanhua Li*, Na Li*, and Bo Tang, Imaging strategies for receptor tyrosine kinase dimers in living cells. Anal. Bioanal. Chem., 2023, 415 (1), 67-82.

8. Yanhua Li†, Kun Tang†, Xia Zhang, Wei Pan, Na Li*, and Bo Tang*, Tumor microenvironment responsive nanocarriers for gene therapy. Chem. Commun., 2022, 58 (63), 8754-8765.

9. Xia Zhang†, Shenglin Wang†, Kun Tang, Wei Pan, Huanjun Xu, Yanhua Li*, Yanan Gao*, Na Li*, and Bo Tang*, Cu²⁺ Embedded Three-Dimensional Covalent Organic Framework for Multiple ROS-Based Cancer Immunotherapy. ACS Appl. Mater. Interfaces, 2022, 14 (27), 30618-30625.

10. Yanhua Li†, Xiaohan Liu†, Xia Zhang, Wei Pan, Na Li*, and Bo Tang*, Immunogenic cell death inducers for enhanced cancer immunotherapy. Chem. Commun., 2021, 57 (91), 12087-12097.

11. Yanhua Li† Xia Zhang†, Xiaohan Liu, Wei Pan, Na Li*, and Bo Tang*, A mineralization strategy based on T-cell membrane coated CaCO₃ nanoparticles against breast cancer and metastasis. Mater. Chem. Front., 2021, 5 (15), 5738-5745.

12. Yanhua Li†, Xia Zhang†, Wei Pan, Na Li*, and Bo Tang*, A Nongenetic Proximity-Induced FRET Strategy Based on DNA Tetrahedron for Visualizing the Receptor Dimerization. Anal. Chem., 2020, 92 (17), 11921-11926.

13. Yanhua Li†, Xiaohan Liu†, Wei Pan, Na Li*, and Bo Tang*, Photothermal therapy-induced immunogenic cell death based on natural melanin nanoparticles against breast cancer. Chem. Commun., 2020, 56 (9), 1389-1392.

14. Yanhua Li†, Na Li†, Wei Pan, Zhengze Yu, Limin Yang, and Bo Tang*, Hollow Mesoporous Silica Nanoparticles with Tunable Structures for Controlled Drug Delivery. ACS Appl. Mater. Interfaces, 2017, 9 (3), 2123-2129.

15. Yanhua Li, Yuanyuan Chen, Wei Pan, Zhengze Yu, Limin Yang, Hongyu Wang, Na Li*, and Bo Tang*, Nanocarriers with multi-locked DNA valves targeting intracellular tumor-related mRNAs for controlled drug release. Nanoscale, 2017, 9 (44), 17318-17324.

16. Yanhua Li†, Xia Zhang†, Xiaohan Liu, Wei Pan, Na Li*, and Bo Tang*, Designing and Engineering of Nanocarriers for Bioapplication in Cancer Immunotherapy. ACS Appl. Bio Mater., 2020, 3 (12), 8321-8337.

研究课题

国家自然科学基金青年基金项目

项目负责人，2023.01-2025.12

山东省自然科学基金青年基金项目

项目负责人，2022.01-2024.12

荣誉称号

山东省高等学校科学技术奖一等奖（第五位）

山东省教育厅

山东省研究生优秀成果一等奖（第一位）

山东省教育厅