李延安

职称：

副教授

专业：

无机化学

博（硕）导：

硕导

最终学历：

博士

联系电话：

电子邮件：

yananli@sdnu.edu.cn

简历及研究领域

李延安，2016年于山东师范大学获得博士学位并留校工作。现从事超分子组装化学的研究工作，主要研究配位作用驱动的组装体金属-有机框架（MOFs）、共价有机框架（COFs）的微纳化合成、结构及在生物医学方面的应用。在Angew. Chem. Int. Ed, ACS Nano, J. Mater. Chem. A, Chem. Commun.等国际学术期刊发表SCI论文40余篇，引用2000余次，H指数为28。主持国家自然科学基金一项，山东省自然科学基金一项。

代表性论文

19. Yan-An Li^‡, Jing-Jing Wan^‡, Wen-Yan Li, Qun Guan, and Yu-Bin Dong*, A covalent organic framework-based nanoreactor for enhanced photothermal therapy via inhibiting intracellular heat defense systems. Chem. Commun. 2023, 59(15), 7463–7466. 原文链接

18. Xiao-Jie Dong, Wen-Yan Li, Qun Guan, Yan-An Li* and Yu-Bin Dong*, A CuS- and BODIPY-Loaded Nanoscale Covalent Organic Framework for Synergetic Photodynamic and Photothermal Therapy. Chem. Commun. 2022, 58(14), 2387–2390. 原文链接

17. Wen-Yan Li^‡, Chao-Wei Zhao^‡, Yue-Feng Zhang, Qun Guan, Jing-Jing Wan, Jian-Ping Ma, Yan-An Li* and Yu-Bin Dong*, A Metal–Organic Cage-Based Nanoagent for Enhanced Photodynamic Antitumor Therapy. Chem. Commun. 2021, 57(64), 7954–7957. 原文链接

16. Qun Guan, Le-Le Zhou, Fan-Hong Lv, Wen-Yan Li, Yan-An Li* and Yu-Bin Dong*, A Glycosylated Covalent Organic Framework Equipped with BODIPY and CaCO₃ for Synergistic Tumor Therapy. Angew. Chem. Int. Ed. 2020, 59(41), 18042–18047. 原文链接

15. Qun Guan, Le-Le Zhou, Wen-Yan Li, Yan-An Li* and Yu-Bin Dong*, Covalent Organic Frameworks (COFs) for Cancer Therapeutics. Chem. Eur. J. 2020, 26(25), 5583–5591. 原文链接

14. Qun Guan, Le-Le Zhou, Li-Na Zhou, Mengdi Li, Guo-Xin Qin, Wen-Yan Li, Yan-An Li* and Yu-Bin Dong*, A Carbon Nanomaterial Derived from a Nanoscale Covalent Organic Framework for Photothermal Therapy in the NIR-II Biowindow. Chem. Commun. 2020, 56(56), 7793–7796. 原文链接

13. Qun Guan^‡, Le-Le Zhou^‡, Yan-An Li*, Wen-Yan Li, Shumei Wang, Chun Song and Yu-Bin Dong*, Nanoscale Covalent Organic Framework for Combinatorial Antitumor Photodynamic and Photothermal Therapy. ACS Nano 2019, 13(11), 13304-13316. 原文链接

12. Qun Guan, Le-Le Zhou, Yan-An Li* and Yu-Bin Dong*, A nanoscale metal–organic framework for combined photodynamic and starvation therapy in treating breast tumors. Chem. Commun. 2019, 55(99), 14898-14901. (Highlighted by Back Cover) 原文链接

11. Wen-Yan Li^‡, Song Yang‡, Yan-An Li*, Qian-Ying Li, Qun Guan and Yu-Bin Dong*, Synthesis of MOF-based Hg²⁺-fluorescence probe via stepwise post-synthetic modification in a single-crystal-to-single-crystal fashion and its application in bioimaging. Dalton Trans. 2019, 48(44), 16502-16508. (Highlighted by Front Cover, and this article is part of the themed collection: Dalton Trans. HOT Articles) 原文链接

10. Qian-Ying Li, Yan-An Li*, Qun Guan, Wen-Yan Li, Xiao-Jie Dong and Yu-Bin Dong*, UiO-68-PT MOF-Based Sensor and Its Mixed Matrix Membrane for Detection of HClO in Water. Inorg. Chem. 2019, 58(19), 9890−9896. (Highlighted by Supplementary Cover). 原文链接

9. Qun, Guan, Dan-Dan Fu, Yan-An Li*, Xiang-Mei Kong, Zhi-Yuan Wei, Wen-Yan Li, Shao-Jun Zhang* and Yu-Bin Dong*, BODIPY-Decorated Nanoscale Covalent Organic Frameworks for Photodynamic Therapy. iScience 2019, 14, 180–198. 原文链接

8. Qun, Guan, Le-Le Zhou, Yan-An Li* and Yu-Bin Dong*, Diiodo-Bodipy-Encapsulated Nanoscale Metal–Organic Framework for PH-Driven Selective and Mitochondria Targeted Photodynamic Therapy. Inorg. Chem. 2018, 57(16), 10137–10145. 原文链接

7. Qun, Guan, Yan-An Li*, Wen-Yan Li and Yu-Bin Dong*, Photodynamic Therapy Based on Nanoscale Metal-Organic Frameworks: From Material Design to Cancer Nanotherapeutics. Chem. Asian J. 2018, 13(21), 3122–3149. 原文链接

6. Yan-An Li^§, Song Yang^§, Qian-Ying Li, Jian-Ping Ma, Shanjun Zhang* and Yu-Bin Dong*, UiO-68-Ol NMOF-Based Fluorescent Sensor for Selective Detection of HClO and Its Application in Bioimaging. Inorg. Chem. 2017, 56(21), 13241–13248. 原文链接

5. Yan-An Li, Xiao-Dong Zhao, Hai-Peng Yin, Song Yang, Gong-Jun Chen and Yu-Bin Dong*, A drug-loaded nanoscale metal-organic framework with a tumor targeting agent for highly effective hepatoma therapy. Chem. Commun. 2016, 52, 14113–14116. 原文链接

4. Yan-An Li, Song Yang, Qi-Kui Liu, Gong-Jun Chen, Jian-Ping Ma and Yu-Bin Dong*, Pd(0)@UiO-68-AP: chelating-directed bifunctional heterogeneous catalyst for stepwise organic transformations. Chem. Commun. 2016, 52, 6517–6520. (Highlighted by Back Cover). 原文链接

3. Yan-An Li, Chao-Wei Zhao, Neng-Xiu Zhu, Qi-Kui Liu, Gong-Jun Chen, Jian-Biao Liu, Xiao-Dong Zhao, Jian-Ping Ma, Shaojun Zhang* and Yu-Bin Dong*, Nanoscale UiO-MOFs- based luminescent sensors for highly selective detection of cysteine and glutathione and their application in bioimaging. Chem. Commun. 2015, 51, 17672–17675. 原文链接

2. Yan-An Li, Fan Yang, Zhao-Cai Liu, Qi-Kui Liu, Yu-Bin Dong*, A porous Cd(II)-MOF-coated quartz fiber for solid-phase microextraction of BTEX. J. Mater. Chem. A 2014, 2(34), 13868–13872. (Highlighted by Back Cover). 原文链接

1. Yan-An Li, Shu-Kui Ren, Qi-Kui Liu, Jian-Ping Ma, Xueyuan Chen, Haomiao Zhu and Yu-Bin Dong*, Encapsulation and Sensitization of UV−vis and Near Infrared Lanthanide Hydrate Emitters for Dual- and Bimodal-Emissions in Both Air and Aqueous Media Based on a Porous Heteroatom-Rich Cd(II)-Framework. Inorg. Chem. 2012, 51(18), 9629–9635. 原文链接

研究课题

国家自然科学基金青年项目

纳米MOFs用于肿瘤靶向双光子光动力治疗的研究。

山东省自然科学基金博士基金项目

纳米尺度MOFs的合成及其在生物成像方面的研究。